unbound to other proteins and is “free” to work inside the body. “Low levels of testosterone impact many aspects of male physiology,” said Andre B. Araujo. Ph. D. a investigate scientist at the New England Research Institutes in Watertown. crowd. and lead author of the study. “This is particularly significant because the ongoing aging of the U. S male population is likely to cause the number of men suffering from
that may impact sex hormone levels. Among all men in the study (mean age 47.3 plus-or-minus 12.5 years) approximately 24 percent had low be testosterone and 11 percent had low levels of free testosterone. Interestingly while low testosterone levels were associated with symptoms many men with low testosterone levels were asymptomatic (e g. among men aged 50 years and older 47.6 percent were asymptomatic).
“Since these men would not likely go to clinical attention,” said Araujo. “it may be important to determine whether there are clinical risks to missing these asymptomatic men with low testosterone levels.” Overall only 5.6 percent of men in the study had symptomatic androgen deficiency. For those men in the upper range of ages in the study (70 years or older) however the percentage increased to 18.4 percent.
The researchers predicted that by the year 2025 there may be as many as 6.5 million American men 30-79 years of age with symptomatic androgen deficiency an increase of 38 percent from year 2000 population estimates.
“This study did not assess whether men with symptomatic androgen deficiency are good candidates for testosterone therapy,” said Araujo. “come up designed randomized placebo controlled trials would be needed to communicate the risks and benefits of testosterone therapy.”
and Digestive and Kidney Diseases (give DK 56842). Analyses for the current study were supported through an unrestricted educational grant from GlaxoSmithKline.
A rapid channel version of this cover has been published on-line and ordain be in the November 2007 air of the Journal of Clinical Endocrinology & Metabolism a publication of The Endocrine Society.
Founded in 1916. The Endocrine Society is the world’s oldest largest and most active organization devoted to investigate on hormones and the clinical learn of endocrinology. Today. The Endocrine Society’s membership consists of over 14,000 scientists physicians educators nurses and students in more than 80 countries. Together these members be all basic applied and clinical interests in endocrinology. The Endocrine Society is based in annoy Chase. Maryland. To learn more about the Society and the handle of endocrinology tour our web place at http://www endo-society org.
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